
Evidence-Based Endodontics
Advancing Endodontic Practice Through Evidence-Based Research
Our Mission
A resource for the endodontic community
Endodontic Evidence publishes literature reviews synthesizing current endodontic research and detailed case studies to advance knowledge in endodontics. We serve dental students, practicing dentists, academic organizations, or anyone interested in the field of endodontics seeking clear, rigorous, and clinically relevant scholarship.
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Literature Reviews
Critical syntheses of current research, distilling the evidence behind modern endodontic practice.

Case Studies
Documented clinical cases with diagnosis, technique, and outcomes — practical insight from real treatment.
Latest Content
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How Large Should We Prepare? Does Apical Preparation Size Affect Endodontic Treatment Outcomes?
Read more →: How Large Should We Prepare? Does Apical Preparation Size Affect Endodontic Treatment Outcomes?The size of the apical preparation is an important component of root canal treatment for a multitude of reasons. It impacts the effectiveness of both instrumentation and irrigation within the…
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Working Length: Electronic Apex Locators or Radiographs?
Read more →: Working Length: Electronic Apex Locators or Radiographs?Working length is one of the most important measurements in root canal treatment because it determines how far instrumentation and obturation extend within the root canal system. Accurate working-length determination…
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One Visit or Two? Evaluating Outcomes in Endodontic Treatment
Read more →: One Visit or Two? Evaluating Outcomes in Endodontic TreatmentRoot canal treatment can be completed in a single appointment or across multiple visits, often with an intracanal medicament such as calcium hydroxide placed between appointments. Multiple-visit treatment has traditionally…
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Sealer Extrusion: Does It Affect Endodontic Outcomes?
Read more →: Sealer Extrusion: Does It Affect Endodontic Outcomes?During root canal treatment, a small amount of root canal sealer was unintentionally extruded into the periapical tissues during obturation. This case raises important clinical questions: Does apical extrusion of…
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Irrigation: Does NaOCl Concentration Really Matter?
Read more →: Irrigation: Does NaOCl Concentration Really Matter?Sodium hypochlorite remains the standard irrigant in endodontics because it provides both broad-spectrum antimicrobial activity and organic tissue dissolution. Successful root canal treatment depends on eliminating microorganisms and removing pulpal…
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MB2 in Maxillary First Molars: What the Literature Tells Us
Read more →: MB2 in Maxillary First Molars: What the Literature Tells UsYou finish a maxillary first molar root canal. The obturation looks great, the patient is asymptomatic, and everything seems successful. Two years later, the tooth presents with a persistent periapical…
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